Publications

/ Nos publications majeures

  • Mesirca P, Chemin J, Barrère C, Torre E, Gallot L, Monteil A, Bidaud I, Diochot S, Lazdunski M, Soong TW, Barrère-Lemaire S, Mangoni ME, Nargeot J (2024) Selective blockade of Cav1.2 (α1C) versus Cav1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine. Nat Commun 15:54.
  • Sekssaoui M, Bockaert J, Marin P, Bécamel C (2024) Antidepressant-like effects of psychedelics in a chronic despair mouse model: is the 5-HT2A receptor the unique player? Neuropsychopharmacology 49:747-756.
  • Monteil A, Guérineau NC, Gil-Nagel A, Parra-Diaz P, Lory P, Senatore A (2024) New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN. Physiol Rev 104:399-472.
  • Barrère-Lemaire S, Vincent A, Jorgensen C, Piot C, Nargeot J, Djouad F (2024) Mesenchymal stromal cells for improvement of cardiac function following acute myocardial infarction: a matter of timing. Physiol Rev 104:659-725.
  • Philibert CE, Disdier C, Lafon PA, Bouyssou A, Oosterlaken M, Galant S, Pizzoccaro A, Tuduri P, Ster J, Liu J, Kniazeff J, Pin JP, Rondard P, Marin P, Vandermoere F (2024) TrkB receptor interacts with mGlu2 receptor and mediates antipsychotic-like effects of mGlu2 receptor activation in the mouse. Sci Adv 10:eadg1679.
  • Maldonado IL, Descoteaux M, Rheault F, Zemmoura I, Benn A, Margulies D, Boré A, Duffau H, Mandonnet E (2024) Multimodal study of multilevel pulvino-temporal connections: a new piece in the puzzle of lexical retrieval networks. Brain 147:2245-2257.
  • Dromard Y, Borie AM, Chakraborty P, Muscatelli F, Guillon G, Desarménien MG, Jeanneteau F (2024) Disengagement of somatostatin neurons from lateral septum circuitry by oxytocin and vasopressin restores social-fear extinction and suppresses aggression outbursts in Prader-Willi syndrome model. Biol Psychiatry 95:785-799.
  • Cresto N, Courret M, Génin A, Pauline Martin CM, Bourret J, Sakkaki S, de Bock F, Janvier A, Polizzi A, Payrastre L, Ellero-Simatos S, Audinat E, Perroy J, Marchi N (2024) Continuous low-level dietary exposure to glyphosate elicits dose and sex-dependent synaptic and microglial adaptations in the rodent brain. Environ Pollut 345:123477.
  • Parmentier ML, Weiss K, Aroua A, Betry C, Rivière M, Navarro O (2024) The influence of environmental crisis perception and trait anxiety on the level of eco-worry and climate anxiety. J Anxiety Disord 101:102799.
  • Xu C, Zhou Y, Liu Y, Lin L, Liu P, Wang X, Xu Z, Pin JP, Rondard P, Liu J (2024) Specific pharmacological and Gi/o protein responses of some native GPCRs in neurons. Nat Commun 15:1990.
  • Tikhomirov R, Oakley RH, Anderson C, Xiang Y, Al Othman S, Smith M, Yaar S, Torre E, Li J, Wilson LR, Goulding DR, Donaldson I, Harno E, Soattin L, Shiels HA, Morris GM, Zhang H, Boyett MR, Cidlowski JA, Mesirca P, Mangoni ME, D’Souza A (2024) Cardiac GR Mediates the Diurnal Rhythm in Ventricular Arrhythmia Susceptibility. Circ Res 134:1306-1326.
  • Hinsinger G, Du Trieu De Terdonck L, Urbach S, Salvetat N, Rival M, Galoppin M, Ripoll C, Cezar R, Laurent-Chabalier S, Demattei C, Agherbi H, Castelnovo G, Lehmann S, Rigau V, Marin P, Thouvenot E (2024) CD138 as a Specific CSF Biomarker of Multiple Sclerosis. Neurol Neuroimmunol Neuroinflamm 11:e200230.
  • Defaye M, Bradaia A, Abdullah NS, Agosti F, Iftinca M, Delanne-Cuménal M, Soubeyre V, Svendsen K, Gill G, Ozmaeian A, Gheziel N, Martin J, Poulen G, Lonjon N, Vachiery-Lahaye F, Bauchet L, Basso L, Bourinet E, Chiu IM, Altier C (2024) Induction of antiviral interferon-stimulated genes by neuronal STING promotes the resolution of pain in mice. J Clin Invest 134:e176474.
  • Ndjim M, Gasmi I, Herbert F, Joséphine C, Bas J, Lamrani A, Coutry N, Henry S, Zimmermann VS, Dardalhon V, Campillo Poveda M, Turtoi E, Thirard S, Forichon L, Giordano A, Ciancia C, Homayed Z, Pannequin J, Britton C, Devaney E, McNeilly TN, Berrard S, Turtoi A, Maizels RM, Gerbe F, Jay P (2024) Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity. Immunity 57:1260-1273.e7.
  • Chaudun F, Python L, Liu Y, Hiver A, Cand J, Kieffer BL, Valjent E, Lüscher C (2024) Distinct µ-opioid ensembles trigger positive and negative fentanyl reinforcement. Nature 630:141-148.
  • Chirayath TW, Ollivier M, Kayatekin M, Rubera I, Pham CN, Friard J, Linck N, Hirbec H, Combes C, Zarka M, Lioté F, Richette P, Rassendren F, Compan V, Duranton C, Ea HK (2024) Activation of osmo-sensitive LRRC8 anion channels in macrophages is important for micro-crystallin joint inflammation. Nat Commun 15:8179.
  • Borie AM, Dromard Y, Chakraborty P, Fontanaud P, Hervé-André E, François A, Colson P, Muscatelli F, Guillon G, Desarménien MG, Jeanneteau F (2024) Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model. Cell Rep Med 5:101781.
  • Naudé J, Sarazin MXB, Mondoloni S, Hannesse B, Vicq E, Amegandjin F, Mourot A, Faure P, Delord B (2024) Dopamine builds and reveals reward-associated latent behavioral attractors. Nat Commun 15:9825.
  • Huang W, Jin N, Guo J, Shen C, Xu C, Xi K, Bonhomme L, Quast RB, Shen DD, Qin J, Liu YR, Song Y, Gao Y, Margeat E, Rondard P, Pin JP, Zhang Y, Liu J (2024) Structural basis of orientated asymmetry in a mGlu heterodimer. Nat Commun 15:10345.
  • Paillé V, Park J, Toutain B, Bourreau J, Fontanaud P, De Nardi F, Gabillard-Lefort C, Bréard D, Guilet D, Henrion D, Legros C, Guérineau NC (2024) Adaptive remodeling of rat adrenomedullary stimulus-secretion coupling in a chronic hypertensive environment. Cell Mol Life Sci, in press.
  • Qebibo L, Davakan A, Nesson-Dauphin M, Boulali N, Siquier-Pernet K, Afenjar A, Amiel J, Bartholdi D, Barth M, Blondiaux E, Cristian I, Frazier Z, Goldenberg A, Good JM, Salussolia CL, Sahin M, McCullagh H, McDonald K, McRae A, Morrison J, Pinner J, Shinawi M, Toutain A, Vyhnálková E, Wheeler PG, Wilnai Y, Hausman-Kedem M, Coolen M, Cantagrel V, Burglen L, Lory P (2024) The characterization of new de novo CACNA1G variants affecting the intracellular gate of Cav3.1 channel broadens the spectrum of neurodevelopmental phenotypes in SCA42ND. Genet Med, in press.
  • Cannone G, Berto L, Malhaire F, Ferguson G, Fouillen A, Balor S, Font-Ingles J, Llebaria A, Goudet C, Kotecha A, Vinothkumar KR, Lebon G (2024) Conformational diversity in class C GPCR positive allosteric modulation. Nat Commun, in press.
  • Odelin G, Faucherre A, Marchese D, Pinard A, Jaouadi H, Le Scouarnec S; FranceGenRef Consortium; Chiarelli R, Achouri Y, Faure E, Herbane M, Théron A, Avierinos JF, Jopling C, Collod-Béroud G, Rezsohazy R and Zaffran S (2023) Variations in the poly-histidine repeat motif of HOXA1 contribute to bicuspid aortic valve in mouse and zebrafish. Nat Commun 14:1543.
  • Romanò N, Lafont C, Campos P, Guillou A, Fiordelisio T, Hodson DJ, Mollard P and Schaeffer M (2023) Median eminence blood flow influences food intake by regulating ghrelin access to the metabolic brain. JCI Insight 8:e165763.
  • Ng S, Valdes PA, Moritz-Gasser S, Lemaitre A-L, Duffau H and Herbet G (2023) Intraoperative functional remapping unveils evolving patterns of cortical plasticity. Brain awad116.
  • Dupuy V, Prieur M, Pizzoccaro A, Margarido C, Valjent E, Bockaert J, Bouschet T, Marin P, Chaumont-Dubel S (2023) Spatiotemporal dynamics of 5-HT6 receptor ciliary localization during mouse brain development. Neurobiol Dis 176:105949.
  • Lengvenyte A, Belzeaux R, Olié E, Hamzeh-Cognasse H, Sénèque M, Strumila R, Cognasse F, Courtet P (2023) Associations of potential plasma biomarkers with suicide attempt history, current suicidal ideation and subsequent suicidal events in patients with depression: A discovery study. Brain Behav Immun 114:242-254.
  • Coutry N, Nguyen J, Soualhi S, Gerbe F, Meslier V, Dardalhon V, Almeida M, Quinquis B, Thirion F, Herbert F, Gasmi I, Lamrani A, Giordano A, Cesses P, Garnier L, Thirard S, Greuet D, Cazevieille C, Bernex F, Bressuire C, Winton D, Matsumoto I, Blottière HM, Taylor N and Jay P (2023) Cross talk between Paneth and tuft cells drives dysbiosis and inflammation in the gut mucosa. Proc Natl Acad Sci U S A 120:e2219431120.
  • Zaïmia N, Obeid J, Varrault A, Sabatier J, Broca C, Gilon P, Costes S, Bertrand G, Ravier MA (2023) GLP-1 and GIP receptors signal through distinct β-arrestin 2-dependent pathways to regulate pancreatic β cell function. Cell Rep 42:113326.
  • Garcia V, Blaquiere M, Janvier A, Cresto N, Lana C, Genin A, Hirbec H, Audinat E, Faucherre A, Barbier EL, Hamelin S, Kahane P, Jopling C, Marchi N (2023) PIEZO1 expression at the glio-vascular unit adjusts to neuroinflammation in seizure conditions. Neurobiol Dis 187:106297.
  • Ihme H, Courtet P, Risch N, Dubois J, Belzeaux R, Olié E (2023) Mediation effect of anxious attachment on relationship between childhood trauma and suicidal ideation sensitive to psychological pain levels. Eur Psychiatry 66:e79.
  • Hua J, Garcia de Paco E, Linck N, Maurice T, Desrumaux C, Manoury B, Rassendren F, Ulmann L (2023) Microglial P2X4 receptors promote ApoE degradation and contribute to memory deficits in Alzheimer’s disease. Cell Mol Life Sci 80:138.
  • Sakkaki S, Cresto N, Chancel R, Jaulmes M, Zub E, Blaquière M, Sicard P, Maurice T, Ellero-Simatos S, Gamet-Payrastre L, Marchi N, Perroy J (2023) Dual-Hit: Glyphosate exposure at NOAEL level negatively impacts birth and glia-behavioural measures in heterozygous shank3 mutants. Environ Int 180:108201.
  • Nakhle J, Khattar K, Özkan T, Boughlita A, Abba Moussa D, Darlix A, Lorcy F, Rigau V, Bauchet L, Gerbal-Chaloin S, Daujat-Chavanieu M, Bellvert F, Turchi L, Virolle T, Hugnot JP, Buisine N, Galloni M, Dardalhon V, Rodriguez AM, Vignais ML (2023) Mitochondria transfer from mesenchymal stem cells confers chemoresistance to glioblastoma stem cells through metabolic rewiring. Cancer Res Commun 3:1041-1056.
  • Yadav A, Matson KJE, Li L, Hua I, Petrescu J, Kang K, Alkaslasi MR, Lee DI, Hasan S, Galuta A, Dedek A, Ameri S, Parnell J, Alshardan MM, Qumqumji FA, Alhamad SM, Wang AP, Poulen G, Lonjon N, Vachiery-Lahaye F, Gaur P, Nalls MA, Qi YA, Maric D, Ward ME, Hildebrand ME, Mery PF, Bourinet E, Bauchet L, Tsai EC, Phatnani H, Le Pichon CE, Menon V, Levine AJ (2023) A cellular taxonomy of the adult human spinal cord. Neuron 111:328-344.e7.
  • Lecat-Guillet N, Quast RB, Liu H, Bourrier E, Møller TC, Rovira X, Soldevila S, Lamarque L, Trinquet E, Liu J, Pin JP, Rondard P, Margeat E (2023) Concerted conformational changes control metabotropic glutamate receptor activity. Sci Adv 9:eadf1378.
  • Persistence of FoxJ1+ Pax6+ Sox2+ ependymal cells throughout life in the human spinal cord.Ripoll C, Poulen G, Chevreau R, Lonjon N, Vachiery-Lahaye F, Bauchet L, Hugnot JP (2023). Persistence of FoxJ1+ Pax6+ Sox2+ ependymal cells throughout life in the human spinal cord. Cell Mol Life Sci 80:181.
  • Bousseyrol E, Didienne S, Takillah S, Solié C, Come M, Ahmed Yahia T, Mondoloni S, Vicq E, Tricoire L, Mourot A, Naudé J, Faure P (2023) Dopaminergic and prefrontal dynamics co-determine mouse decisions in a spatial gambling task. Cell Rep 42:112523.
  • Cutando L, Puighermanal E, Castell L, Tarot P, Belle M, Bertaso F, Arango-Lievano M, Ango F, Rubinstein M, Quintana A, Chédotal A, Mameli M and Valjent E (2022) Cerebellar dopamine D2 receptors regulate social behaviors. Nat Neurosci 25:900-911.
  • Conejero I, Collombier L, Lopez-Castroman J, Mura T, Alonso S, Olié E, Boudousq V, Boulet F, Arquizan C, Boulet C, Wacongne A, Heitz C, Castelli C, Mouchabac S, Courtet P, Abbar M and Thouvenot E (2022) Association between brain metabolism and clinical course of motor functional neurological disorders. Brain 145:3264-3273.
  • Huzard D, Martin M, Maingret F, Chemin J, Jeanneteau F, Mery PF, Fossat P, Bourinet E and François A (2022) The impact of C-tactile low-threshold mechanoreceptors on affective touch and social interactions in mice. Sci Adv 8:eabo7566.
  • Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP and Rondard P (2022) Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain. Nat Chem Biol 18:894-903.
  • Sarre C, Contreras-Lopez R, Nernpermpisooth N, Barrere C, Bahraoui S, Terraza C, Tejedor G, Vincent A, Luz-Crawford P, Kongpol K, Kumphune S, Piot C, Nargeot J, Jorgensen C, Djouad F and Barrere-Lemaire S (2022) PPARβ/δ priming enhances the anti-apoptotic and therapeutic properties of mesenchymal stromal cells in myocardial ischemia-reperfusion injury. Stem Cell Res Ther 13:167.
  • Brown MR, Laouteouet D, Delobel M, Villard O, Broca C, Bertrand G, Wojtusciszyn A, Dalle S, Ravier MA, Matveyenko AV and Costes S (2022) The nuclear receptor REV-ERBα is implicated in the alteration of β-cell autophagy and survival under diabetogenic conditions. Cell Death Dis 13:353.
  • Herbet G and Duffau H (2022) Contribution of the medial eye field network to the voluntary deployment of visuospatial attention. Nat Commun 13:328.
  • Healey RD, Saied EM, Cong X, Karsai G, Gabellier L, Saint-Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C and Granier S (2022) Discovery and Mechanism of Action of Small Molecule Inhibitors of Ceramidases. Angew Chem Int Ed Engl 61:e202109967.
  • Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B and Bron P (2022) Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex. Sci Adv 8:eabo7761.
  • Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, Banala S, Freeman M, Xu CS, Kirchhausen T, Hess HF, Lavis L, Li Y, Chaumont-Dubel S and Clapham DE (2022) A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell 185:3390-3407.e18.
  • Liu J, Tang H, Xu C, Zhou S, Zhu X, Li Y, Prézeau L, Xu T, Pin J-P, Rondard P, Ji W and Liu J (2022) Biased signaling due to oligomerization of the G protein-coupled platelet-activating factor receptor. Nat Commun 13:6365.
  • El Cheikh Hussein L, Fontanaud P, Mollard P and Bonnefont X (2022) Nested calcium dynamics support daily cell unity and diversity in the suprachiasmatic nuclei of free-behaving mice. PNAS Nexus 1:pgac112.
  • Sengupta S, Mondal M, Prasasvi KR, Mukherjee A, Magod P, Urbach S, Friedmann-Morvinski D, Marin P and Somasundaram K (2022) Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth. Elife 11:e78972.
  • Dromard Y, Arango-Lievano M, Borie A, Dedin M, Fontanaud P, Torrent J, Garabedian MJ, Ginsberg SD and Jeanneteau F (2022) Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway. Acta Neuropathol Commun 10:91.
  • Hemonnot-Girard AL, Meersseman C, Pastore M, Garcia V, Linck N, Rey C, Chebbi A, Jeanneteau F, Ginsberg SD, Lachuer J, Reynes C, Rassendren F and Hirbec H (2022) Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice. J Neuroinflammation 19:234.
  • Pereira V, Arias JA, Llebaria A and Goudet C (2022) Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain. Pharmacol Res 187:106602.
  • Moutin E, Sakkaki S, Compan V, Bouquier N, Giona F, Areias J, Goyet E, Hemonnot-Girard AL, Seube V, Glasson B, Benac N, Chastagnier Y, Raynaud F, Audinat E, Groc L, Maurice T, Sala C, Verpelli C and Perroy J (2021) Restoring glutamate receptosome dynamics at synapses rescues autism-like deficits in Shank3-deficient mice. Mol Psychiatry 26:7596-7609.
  • Borie AM, Dromard Y, Guillon G, Olma A, Manning M, Muscatelli F, Desarménien MG aand Jeanneteau F (2021) Correction of vasopressin deficit in the lateral septum ameliorates social deficits of mouse autism model. J Clin Invest 131:e144450.
  • Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, Zhou Y, Pin JP, Rondard P, Liu H, Liu J, Sun F, Wu B and Zhao Q (2021) Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature 594:589-593.
  • Shen C, Mao C, Xu C, Jin N, Zhang H, Shen DD, Shen Q, Wang X, Hou T, Chen Z, Rondard P, Pin JP, Zhang Y and Liu J (2021) Structural basis of GABAB receptor-Gi protein coupling. Nature 594:594-598.
  • Relier S, Ripoll J, Guillorit H, Amalric A, Achour C, Boissière F, Vialaret J, Attina A, Debart F, Choquet A, Macari F, Marchand V, Motorin Y, Samalin E, Vasseur JJ, Pannequin J, Aguilo F, Lopez-Crapez E, Hirtz C, Rivals E, Bastide A and David A (2021) FTO-mediated cytoplasmic m 6 A m demethylation adjusts stem-like properties in colorectal cancer cell. Nat Commun 12:1716.
  • Cao AM, Quast RB, Fatemi F, Rondard P, Pin JP and Margeat E (2021) Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state. Nat Commun 12:5426.
  • Haubrich J, Font J, Quast RB, Goupil-Lamy A, Scholler P, Nevoltris D, Acher F, Chames P, Rondard P, Prézeau L and Pin JP (2021) A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers. Proc Natl Acad Sci USA 118:e2105848118.
  • Bous J, Orcel H, Floquet N, Leyrat C, Lai-Kee-Him J, Gaibelet G, Ancelin A, Saint-Paul J, Trapani S, Louet M, Sounier R, Déméné H, Granier S, Bron P and Mouillac B (2021) Cryo-electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex. Sci Adv 7:eabg5628.
  • Grison CM, Lambey P, Jeannot S, Del Nero E, Fontanel S, Peysson F, Heuninck J, Sounier R, Durroux T, Leyrat C, Granier S and Bechara C (2021) Molecular insights into mechanisms of GPCR hijacking by Staphylococcus aureus. Proc Natl Acad Sci USA 118:e2108856118.
  • Cong X, Maurel D, Déméné H, Vasiliauskaité-Brooks I, Hagelberger J, Peysson F, Saint-Paul J, Golebiowski J, Granier S and Sounier R (2021) Molecular insights into the biased signaling mechanism of the μ-opioid receptor. Mol Cell 81:4165-4175.e6.
  • Golan M, Boulanger-Weill J, Pinot A, Fontanaud P, Faucherre A, Gajbhiye DS, Hollander-Cohen L, Fiordelisio-Coll T, Martin AO and Mollard P (2021) Synaptic communication mediates the assembly of a self-organizing circuit that controls reproduction. Sci Adv 7:eabc8475.
  • Nasrallah C, Cannone G, Briot J, Rottier K, Berizzi AE, Huang CY, Quast RB, Hoh F, Banères JL, Malhaire F, Berto L, Dumazer A, Font-Ingles J, Gómez-Santacana X, Catena J, Kniazeff J, Goudet C, Llebaria A, Pin JP, Vinothkumar KR and Lebon G (2021) Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep 36:109648.
  • Liu L, Fan Z, Rovira X, Xue L, Roux S, Brabet I, Xin M, Pin JP, Rondard P and Liu J (2021) Allosteric ligands control the activation of a class C GPCR heterodimer by acting at the transmembrane interface. Elife 10:e70188.
  • Martin PY, Doly S, Hamieh AM, Chapuy E, Canale V, Drop M, Chaumont-Dubel S, Bantreil X, Lamaty F, Bojarski AJ, Zajdel P, Eschalier A, Marin P and Courteix C (2020) mTOR activation by constitutively active serotonin6 receptors as new paradigm in neuropathic pain and its treatment. Prog Neurobiol 193:101846.
  • Fumagalli A, Heuninck J, Pizzoccaro A, Moutin E, Koenen J, Séveno M, Durroux T, Junier MP, Schlecht-Louf G, Bachelerie F, Schütz D, Stumm R, Smit M, Guérineau NC, Chaumont-Dubel S, Marin P (2020) The atypical chemokine receptor 3 interacts with Connexin 43 inhibiting astrocytic gap junctional intercellular communication. Nat Commun 11:4855.
  • Liu H, Yi P, Zhao W, Wu Y, Acher F, Pin JP, Liu J, Rondard P (2020) Illuminating the allosteric modulation of the calcium-sensing receptor. Proc Natl Acad Sci USA 117:21711-21722.
  • Berthoux C, Hamieh AM, Rogliardo A, Doucet E, Coudert C, Ango F, Grychowska K, Chaumont-Dubel S, Zajdel P, Maldonado R, Bockaert J, Marin P, Becamel C (2020) Early 5- HT 6 receptor blockade prevents symptom onset in a model of adolescent cannabis abuse. EMBO Mol Med 12:e10605.
  • Kemkem Y, Nasteska D, de Bray A, Bargi-Souza P, Peliciari-Garcia R, Duvoid-Guillou A, Mollard P, Hodson DJ, Schaeffer M (2020) Maternal hypothyroidism in mice influences glucose metabolism in adult offspring. Diabetologia 63:1822-1835.
  • Puighermanal E, Castell L, Esteve-Codina A, Melser S, Kaganovsky K, Zussy C, Boubaker-Vitre J, Gut M, Rialle S, Kellendonk C, Sanz E, Quintana A, Marsicano, G, Martin M, Rubinstein M, Girault JA, Ding JB, Valjent E (2020) Functional and molecular heterogeneity of D2R neurons along dorsal ventral axis in the striatum. Nat Commun 11:1957.
  • Boisguerin P, Covinhes A, Gallot L, Barrère C, Vincent A, Busson M, Piot C, Nargeot J, Lebleu B, Barrère-Lemaire S (2020) A novel therapeutic peptide targeting myocardial reperfusion injury. Cardiovasc Res 116:633-644.
  • Beaulieu-Laroche L, Christin M, Donoghue, A Agosti F, Yousefpour N, Petitjean H, Davidova A, Stanton C, Khan U, Dietz C, Faure E, Fatima T, MacPherson A, Mouchbahani-Constance S, Bisson D, Haglund L, Ouellet J, Stone L, Samson J, Smith MJ, Ask K, Ribeiro-da Silva A, Blunck R, Poole K, Bourinet E, Sharif-Naeini R (2020). TACAN is an ion channel involved in sensing mechanical pain. Cell 180:956-967.e17.
  • Pujol C, Dupuy V, Séveno M, Runtz L, Bockaert J, Chaumont- Dubel S, Marin P (2020) Dynamic interactions of the 5-HT 6 receptor with protein partners control dendritic tree morphogenesis. Sci Signal 13:eaax9520.
  • Rochais C, Lecoutey C, Hamidouche K, Giannoni P, Gaven F, Cem E, Mignani S, Baranger K, Freret T, Bockaert J, Rivera S, Boulouard M, Dallemagne P, Claeysen S (2020) Donecopride, a Swiss army knife with potential interest against Alzheimer’s disease. Br J Pharmacol 177:1988-2005.
  • Champagne J, Linares LK, Maurel B, Zampieri A, Moreno M, Fuentes I, Dubois E, Severac D, Decorsière A, Bienvenu F (2020) TAG-RNAi overcomes off-target effects in cancer models. Oncogene 39:935-945.
  • Sebastianutto I, Goyet E, Andreoli L, Font-Ingles J, Moreno-Delgado D, Bouquier N, Jahannault-Talignani C, Moutin E, Di Menna L, Pin JP, Maslava N, Fagni L, Nicoletti F, Ango F, Cenci MA, Perroy J (2020) D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson’s disease. J Clin Invest 130:1168-1184.
  • Shaye H, Ishchenko A, Lam JH, Han GW, Xue L, Rondard P, Pin JP, Katritch V, Gati C, Cherezov V (2020) Structural basis of metabotropic GABA receptor activation. Nature 584:298-303.
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