Research & Development service

This service, which brings together high-level engineers (1 IR and 2 IE) with complementary expertise, was created in early 2024 to develop new preclinical models and experimental protocols to meet the needs of the projects of the various IGF teams. The technological axes already in place or in the process of being implemented include :
- The development of new functional tests in preclinical models
- Development of stem cell and organoid models
- The generation of new cellular and viral models by genome editing.
The engineers in this service are responsible for assisting the teams in the development of these tools and approaches, and for training team members in these new technologies.
The activities of the R&D service are monitored by a Steering Committee made up of the scientific heads of the engineers in the service and representatives of management.
Manager
Philippe MARIN
IGF staff involved



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2017Accreditation to Supervise Research (HDR) - Univ. Montpellier - France
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2002PhD in Biochemistry/Neurosciences - Univ. Montpellier - France
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2005-Associate professor in Neuroscience - Faculty of Medicine of Montpellier-Nîmes - France
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2002-2005Postdoctoral fellow - Dr. R. Malinow's team - CSHL - NY - USA
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2023Elected member (substitute) of the Human Resources Committee - Biology & Health Scientific Department - Univ. Montpellier
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2022-Appointed Faculty Referent Against Gender-Based and Sexual Violence - Medical School of Montpellier-Nîmes - Univ. Montpellier
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2021-Appointed Handiversity Teacher Referent - Medical School of Montpellier-Nîmes - Univ. Montpellier
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2014-Elected member at the Board of the Medical School of Montpellier-Nîmes - Univ. Montpellier
- I am a neurobiologist. By combining pharmacological, biochemical and proteomic approaches to electrophysiological and behavioural analyses, I developed ambitious projects aimed at characterizing the modulatory role of serotonin receptors on synaptic plasticity and cognitive functions dependent on prefrontal cortex as well as their involvement in psychiatric disorders such as schizophrenia and depression.



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1999Accreditation to Supervise Research (HDR), Life Sciences specialty - Pierre et Marie Curie University - Paris - France
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1992PhD in Molecular and Cellular Pharmacology - Pierre et Marie Curie University - Paris - France
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1988Agrégation of Biochemistry - École Normale Supérieure de Cachan - Paris - France
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2005-Head of the "Neuroproteomics and Signaling in Brain Pathologies" team at the Institute of Functional Genomics (IGF) - Montpellier - France
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2005-Research Director at CNRS
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1993-2005Research fellow at CNRS
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1989-1993PhD student (holder of a fellowship from the Direction des Recherches, Études et Techniques (DRET)
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1985-1989Student at École Normale Supérieure de Cachan - Paris - France
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2021-Director of the Institute of Functional Genomics of Montpellier (21 teams, ~360 people)
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2021-Member representing the CNRS of the "Comité de la Recherche en matière Biomédicale et de Santé Publique (CRBSP)" of Montpellier University Hospital
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2018Director of the IGF Neuroscience Department (12 teams, ~200 people)
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2017-Co-manager of the Neuroscience Axis of the Biology and Health Pole of the University of Montpellier
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2016-2020Member of the FRM Scientific Council
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2014-2017President of the French Proteomics Society (SFEAP)
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2011-2020Director of the Proteome Pole of Montpellier-Languedoc Roussillon (PPM, regional proteomics platform with IBiSA accreditation)
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2011-2020Scientific Manager of the IGF Functional Proteomics Platform, the main site of the PPM
- Following a training in biochemistry, neurobiology and pharmacology, I specialized in proteomics, which my team applies to discover new signaling mechanisms triggered by serotonin and other neurotransmitter receptors, as well as novel regulatory mechanisms of these systems potentially involved in various neurological and psychiatric diseases. We also use proteomics to characterize new biomarkers of these pathologies.



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2012-2013HDR - University of Montpellier - France
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1996-2000Thesis/PhD - Molecular Biology - University of Montpellier - France
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1995-1996DU - Immunology - University of Montpellier - France
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1994-1995Master 2 - Molecular Biology - University of Montpellier - France
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1993-1994Master 1 - Molecular Biology - University of Montpellier - France
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1991-1993Licence - Molecular Biology - University of Montpellier - France
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1989-1991DEUG B - Biology - University of Montpellier - France
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2005-Permanent Researcher (CRCN - CNRS) - Team "Ion Channels in Neuronal Excitability and Diseases"(Dir. P. Lory) - Institut de Génomique Fonctionnelle - Montpellier - France
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2003-2005Permanent Researcher (CR2 - CNRS) - Team "Ion Channels: Structure-fonction and channelopathies" (Dir. P. Lory) - Institut de Génomique Fonctionnelle - Montpellier - France
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2001-2002Permanent Researcher (CR2 - CNRS) Dir. J. Nargeot - Institut de Génétique Humaine - Montpellier - France
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2000-2001Research associate (Dir. Pr. R.J. Miller) - Department of Pharmacology, Neurobiology and Physiology - University of Chicago - USA
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1996-2000Graduate Student (Dir. J. Nargeot) - Institut de Génétique Humaine - Univ. Montpellier - France
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1995-1996Master Student Univ. Montpellier (Dir. Pr. J. Clot) - Hôpital St. Eloi – Department of Immunology - Montpellier - France
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1994-1995Master Student Univ. Montpellier (Dir. Pr. J. Haiech) - Laboratoire de Chimie Bactérienne - CNRS - Marseille - France
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2022-2025Coordinator of the RestoreLeak consortium (https://www.neuron-eranet.eu/projects/RestoreLeak)
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2015-President of the French Ion Channel society (https://www.canaux-ioniques.fr)
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2020-2023Libellas foundation : President of the scientific committee (https://fundacionlibellas.org)
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2021-2026Elected member of the National Committee of the CNRS (Sub-committee #24 "Aging, Tumorigenesis, Physiology")
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2016-2021Idem
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2008-Head of the Vectorology facility of Montpellier - France (UAR BioCampus, https://www.biocampus.cnrs.fr )
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2020-Associate Editor - AllLife
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2020-Review Editor - Frontiers in Molecular Neuroscience
- Ion channels / Physiology / Neurosciences / Human Diseases
- Gene Transfer / Viral Vectors / Genome Editing











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2021PhD Thesis - Neurosciences - Bourgogne Franche Comté University - Dijon - France
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2001MSc. of Physiology – Birkbeck College - London - UK
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1998DUT of Applied Biology - Dijon - France
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2020-IE CNRS, UMR 5203 Institut de Génomique Fonctionnelle - Montpellier - France
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2013-2020IE CNRS, UMR 6265 Centre des Sciences du Goût et de l'Alimentation - Dijon - France
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2002-2013IE CNRS, UMR 7102 Neurobiologie des Processus Adaptatifs - Paris - France
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2002-2002Assistant Engineer, U36, Chair of Experimental Medicine, Collège de France - Paris - France
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1998-2001Research technician in the Department of Anatomy and Developmental Biology at the Royal Free Campus, UCL - London - UK
- Within the UMRs
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2015-2020Quality Manager
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2009-2013Elected member of the Laboratory Council
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2009-2011In charge of genetically modified organism approval applications
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2009-2013Technical manager of A2L2 platform
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2003-2009In charge of L1-L2 culture rooms
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2003-2013Prevention assistant of health and safety
- At CNRS
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2015-2026Full member, appointed by the administration to represent BAP A (Life Sciences) on the national commission for research technicians
- I am involved in the team's research projects, which aim to study the neuronal circuits involved in pain pathophysiology.
- I am specialized in molecular biology techniques (cloning, PCR, QPCR and RNAscope in situ hybridization), biochemistry (western blot and cell fractionation), cell biology (neuronal cultures and immunolabeling), imaging (epifluorescence, confocal and nanozoomer microscopy) and behavioral exploration (olfaction).



