WELCOME
The Institute of Functional Genomics (IGF) is a multidisciplinary research centre which is developing a project focused on the functional genomics of physiological and pathological cellular communications in the fields of neurobiology, endocrinology, oncology and cardiology.
This project is based on a multi-scale strategy from 'molecule to systems' and combines structural, biochemical, genetic, epigenetic, omics, physiological and behavioural studies. A major effort is paid to the development of single-cell studies through multiple dimensions and multi-omic approaches, that are necessary to address the complexity of life.
The project of IGF is increasingly based on translational research, promoted by the recruitment of teams of clinicians from different fields (neurovascular, diabetology, neuro-oncology and psychiatry). The objective is to identify new mechanisms and concepts in the field of cellular communications, in order to develop new therapeutic strategies and diagnostic tools.
CANAUX IONIQUES ET PHYSIOPATHOLOGIE
10h - Oxana Koundouzova: Remodelage du myocarde au cours de l'insuffisance cardiaque: rôle de l'apeline
10h30 - Jacques Barhanin: Le canal K+ TWIK1: sélectivité et métabolisme du fer
11h00 - Sylvie Diochot: Utilisation des toxines animales pour déterminer le rôle des canaux ASIC dans la douleur
11h30 - Flavien Charpentier: Loss-of-function variants on NCX1 gene are associated with early repolarization syndrome and shortened QT interval.
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