WELCOME
The Institute of Functional Genomics (IGF) is a multidisciplinary research centre which is developing a project focused on the functional genomics of physiological and pathological cellular communications in the fields of neurobiology, endocrinology, oncology and cardiology.
This project is based on a multi-scale strategy from 'molecule to systems' and combines structural, biochemical, genetic, epigenetic, omics, physiological and behavioural studies. A major effort is paid to the development of single-cell studies through multiple dimensions and multi-omic approaches, that are necessary to address the complexity of life.
The project of IGF is increasingly based on translational research, promoted by the recruitment of teams of clinicians from different fields (neurovascular, diabetology, neuro-oncology and psychiatry). The objective is to identify new mechanisms and concepts in the field of cellular communications, in order to develop new therapeutic strategies and diagnostic tools.
REGULATION OF NUTRIENT UPTAKE CONTROLS CANCER CELL GROWTH AND METABOLISM
Jeff HOLST
University of Sydney
Dr. Jeff Holst is Faculty at the Centenary Institute, and Associate Professor at the University of Sydney. His laboratory has uncovered how amino acid transporters regulate nutrient uptake in different cancers and cancer subtypes. His recent work continues to determine how these amino acid transporters function in melanoma, breast cancer and prostate cancer, as well as developing novel therapeutics aimed at blocking nutrient uptake in cancer.
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