WELCOME
The Institute of Functional Genomics (IGF) is a multidisciplinary research centre which is developing a project focused on the functional genomics of physiological and pathological cellular communications in the fields of neurobiology, endocrinology, oncology and cardiology.
This project is based on a multi-scale strategy from 'molecule to systems' and combines structural, biochemical, genetic, epigenetic, omics, physiological and behavioural studies. A major effort is paid to the development of single-cell studies through multiple dimensions and multi-omic approaches, that are necessary to address the complexity of life.
The project of IGF is increasingly based on translational research, promoted by the recruitment of teams of clinicians from different fields (neurovascular, diabetology, neuro-oncology and psychiatry). The objective is to identify new mechanisms and concepts in the field of cellular communications, in order to develop new therapeutic strategies and diagnostic tools.
CEREBELLUM-HIPPOCAMPUS INTERACTION FOR NAVIGATION AND SPACE CODING
Laure RONDI-REIG
(Institut de Biologie Paris-Seine)
Laure Rondi-Reig s'intéresse au rôle du cervelet à différents niveaux de la cognition spatiale: l’intégration sensorielle, la construction d'une représentation de son environnement, l'interaction avec cet environnement au cours de la navigation. Ses travaux portent sur le développement d'outils comportementaux, en environnement réel ou virtuel, qui permettent de caractériser les déficits de cognition spatiale dans différentes pathologies (maladie d’Alzheimer, autisme), et sur la dynamique des réseaux cérébraux (cervelet et régions du cerveau antérieur) pendant la navigation.
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